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BioNTech SE

Data period: Annual Quarterly Graham uses annual
NASDAQ · Healthcare
BioNTech SE
BNTX · Biotechnology
$90.89
▼ -1.33 (-1.44%)
Cached · 10 min
Overall Grade
F
Defensive
F
Enterprising
Profitability
F
Gross Profit Margin 39.5%
Operating Margin -568.3%
Net Income Margin -450.4%
Fin. Health
C
Years to Pay Off Debt -0.6 yrs
Working Capital vs Long-Term Debt $13.7B
Working Capital $13.8B
Valuation
B
Price-to-Book 1.23x
Cash Flow
F
Free Cash Flow -$500M
Owner Earnings -$332M
About BioNTech SE
BioNTech SE, together with its subsidiaries, engages in the development and commercialization of immunotherapies in Germany. The company offers BNT162, an mRNA vaccine for the treatment of SARS-CoV-2 virus. It also develops oncology drugs under Phase III clinical trial, including Gotistobart for metastatic non-small cell lung cancer, Pumitamig for small cell lung cancer and advanced/metastatic triple-negative breast cancer, and Trastuzumab pamirtecan for metastatic breast cancer and epirubicin and cyclophosphamide; and drugs under Phase 2/3 clinical trial, such as BNT113 for human papillomavirus and head and neck squamous cell carcinoma, as well as Pumitamig for metastatic colorectal and non-small cell lung cancer. In addition, the company engages in the development of oncology drugs under Phase II clinical trial comprising BNT116 for advance non-small cell lung cancer, BNT326/YL202 for multiple solid tumors and advanced/metastatic breast cancer, Autogene cevumeran for advance colorectal cancer, and Gotistobart for platinum-resistant ovarian cancer, as well as Pumitamig for glioblastoma, hepatocellular carcinoma, malignant pleural mesothelioma, neuroendocrine neoplasms, and metastatic pancreatic ductal adenocarcinoma. Further, it develops BNT166 which is Phase II clinical trial for mpox virus; and infectious diseases drugs under Phase 1/2 clinical trial, which include BNT162 + BNT161 for SARS-CoV-2 and influenza, BNT164 for tuberculosis, BNT165 for malaria, and BNT166 for mpox. The company was incorporated in 2008 and is headquartered in Mainz, Germany.
Metric Explanations
What each dimension measures and where the thresholds come from.
Gross Profit Margin
Revenue minus cost of goods sold. Graham's ≥40% threshold identifies businesses with durable pricing power. Note: software and financial companies naturally exceed this; retailers and manufacturers rarely reach it due to their cost structures.
Operating Margin
Profit after operating costs before interest and taxes. A consistent ≥15% operating margin signals a business with real competitive advantages. Capital-intensive industries (airlines, auto, commodities) rarely hit this threshold due to their structural cost base — compare within industry for context.
Net Income Margin
Bottom-line profit as a percentage of revenue. The ≥20% target reflects Buffett's preference for highly profitable businesses. Financial engineering (buybacks, tax optimisation) can inflate this temporarily — look for consistency across multiple years rather than a single strong result.
Years to Pay Off Debt
Total Debt ÷ Net Income. Lower = stronger balance sheet. Important caveat: utilities, telecoms, REITs, and infrastructure companies carry large structural debt by design — their bond-like cash flows service it comfortably at ratios that would alarm Graham. Compare within sector.
Working Capital vs Long-Term Debt
Working Capital minus Long-Term Debt. Negative results are common and expected in capital-return-focused businesses like Apple, Domino's, and McDonald's — where aggressive buybacks and dividends intentionally reduce book equity. This does not indicate financial distress in high-FCF businesses.
Working Capital
Current Assets minus Current Liabilities. Negative working capital can be a deliberate efficiency strategy in businesses that collect cash before paying suppliers (retailers, fast food franchises, subscription businesses). Assess alongside free cash flow generation for full context.
Price-to-Book
Market price vs book value per share. Rarely below 1.5x for quality businesses today. Intangible assets (brand, software, patents) don't appear on the balance sheet under accounting rules, making P/B artificially high for asset-light companies like software and consumer brands.
Free Cash Flow
Operating cash flow minus capital expenditures. Buffett's most important metric — cash a business actually generates for its owners after maintaining and growing its asset base. Consistently positive FCF is one of the strongest indicators of a durable, well-run business regardless of accounting profits.
Owner Earnings
Net Income + Depreciation & Amortisation − Capital Expenditures. Buffett's preferred measure of a company's true annual earning power — what could theoretically be distributed to owners without impairing the business. More reliable than reported EPS because it accounts for the capital cost of maintaining the business.
Market Cap $23.0B
Enterprise Value $9.2B
P/E (TTM) -17.72
Dividend Yield N/A
Exchange NASDAQ
Gross Profit 39.5%
Operating Margin -568.3%
Net Margin -450.4%
Sector Healthcare
Industry Biotechnology
Employees 7807
Country Germany
Showing Key Metrics
Income Highlights
Metric Q1 2026 Q4 2025 Q4 2024
Gross Profit % 39.5% 63.3% N/A
Operating Margin % -568.3% -30.9% N/A
Net Income % -450.4% -33.6% N/A
Diluted EPS -2.10 -1.25 N/A
Balance Sheet Highlights
Metric Q1 2026 Q4 2025 Q4 2024
Total Assets $21.1B $22.0B N/A
Total Debt $303M $267M N/A
Working Capital $13.8B $14.0B N/A
Years to Pay Debt -0.57 -0.88 N/A
Cash Flow Highlights
Metric Q1 2026 Q4 2025 Q4 2024
Free Cash Flow -$500M $247M N/A
Owner Earnings -$332M -$78M N/A
CapEx % of Net Income N/A N/A N/A
📊 Quarterly mode — Graham Fair Value & 7 Criteria require annual data. Switch to Annual for full analysis.
Quarter vs Same Quarter Last Year
YoY strips seasonality
Revenue Growth (YoY)
Prior year: $183M ▼ $118M -35.4%
Revenue growth vs same quarter last year strips seasonality. Consistent double-digit growth is a Buffett hallmark.
Gross Margin
Prior year: 54.2% ▼ 39.5% -14.6pp
Buffett: consistent gross margin above 40% signals durable pricing power and competitive moat.
Operating Margin
Prior year: -367.2% ▼ -568.3% -201.2pp
Graham: operating margin reflects true business economics before financing. Trend matters as much as level.
Net Margin
Prior year: -227.5% ▼ -450.4% -222.9pp
Net margin can be distorted by one-time items, tax timing, or interest costs — compare to operating margin for signal quality.
Quarterly Health Checks
3 Graham/Buffett criteria that are valid and reliable on quarterly data
❌ Adequate Size
Graham required scale for resilience. Quarterly revenue × 4 gives an annualised proxy.
$118M/qtr (≈$472M ann.)
vs > $1.5B annualised revenue
✅ Financial Condition
Current assets vs current liabilities — a real-time liquidity snapshot. Valid and reliable on quarterly data.
8.80x current ratio
vs ≥ 2.0x
❌ Free Cash Flow
Buffett's most important single metric. A positive FCF quarter means the business generated real cash for owners after maintaining its asset base.
-$500M
vs Positive
Operating Cash Flow
-$421M
Latest quarter · Buffett's cash reality check
ROIC
-2.7%
Based on latest annual operating income
Return on Invested Capital — Buffett's preferred measure for asset-light businesses. ROIC > 15% consistently signals a durable competitive advantage (moat). More meaningful than P/B for software, pharma, and consumer brand companies where most value is intangible and off-balance-sheet.
Market Cap / Net Assets
1.2x
Net Assets: $18.7B
Asset Context — Biotechnology
R&D costs are expensed immediately under GAAP rather than capitalised as assets, meaning a pharma/biotech company's most valuable assets (drug pipeline, patents) are largely invisible on the balance sheet. Net Assets significantly understates true economic value. Pipeline depth and revenue diversification matter more.
⚠️ Net margin compressed 222.9pp vs same quarter last year. Common causes: one-time charges (restructuring, write-downs, legal settlements), tax rate changes, or rising interest expense. Check the income statement notes before drawing conclusions about operating health.
Peers & Industry Comparison
Biotechnology — Auto-detected peers
Company Price Market Cap P/E Gross Margin Net Margin Revenue
BNTX $90.89 $23.0B -17.72 39.5% -450.4% $118M
AMGN
Amgen Inc.
$337.60 $182.2B 23.5 71.4% 21.0% $37.2B
GILD
Gilead Sciences, Inc.
$123.76 $153.7B 16.8 79.4% 31.0% $29.7B
BIIB
Biogen Inc.
$196.58 $29.0B 21.2 78.7% 13.8% $9.9B
REGN
Regeneron Pharmaceuticals, Inc.
$609.94 $63.9B 14.9 43.9% 29.6% $14.9B
VRTX
Vertex Pharmaceuticals Incorpor
$451.63 $114.6B 26.8 54.4% 35.5% $12.2B
"The management of a business is its most important single factor — more important than market position, patents, or financial structure."
— Benjamin Graham
Capital Allocation & Alignment
Insider Ownership
57.13%
High — management has strong skin in the game
Return on Equity (ROE)
-2.8%
Weak — poor returns on equity
Return on Assets (ROA)
-2.5%
Poor — assets are not generating adequate returns
Debt Trend YoY
+13.2% YoY
Debt is growing — management is leveraging up
Leadership Team
Ugur Sahin
Co-Founder, CEO & Chair of the Management Board
Age 60
Pay: $1,222,745
Ozlem Tureci
Co-Founder, Chief Medical Officer & Member of Management Board
Age 58
Pay: $974,719
Ramon Zapata-Gomez
CFO & Member of Management Board
Age 51
Pay: $1,185,657
Sierk Pötting Ph.
MD, COO & Member of Management Board
Age 52
Pay: $1,006,012
Lisa Birringer
Senior Vice President of Global Financial Reporting & Accounting
Top Institutional Holders
Institution % Owned Shares
T. Rowe Price Investment Management, Inc. 2.32% 5,856,073
FMR, LLC 2.26% 5,709,240
Primecap Management Company 1.50% 3,793,711
Flossbach von Storch SE 1.46% 3,680,315
Dodge & Cox Inc. 1.45% 3,676,791
Blackrock Inc. 0.66% 1,658,153
BNP Paribas Financial Markets 0.65% 1,651,789
Temasek Holdings (Private) Ltd 0.60% 1,506,027
Risk Analysis
Beta (Market Risk)
1.32
Moderate volatility — moves slightly more than market
Short Interest
3.3% of float
Low short interest — market is not heavily bearish
Debt-to-Equity
0.02x
Conservative balance sheet — low financial risk
Current Ratio
8.80x
Strong liquidity — Graham approved
52-Week Price Range
Low: $79.52 Current: $90.89 High: $124.00
Currently at 26% of 52-week range

BioNTech SE (BNTX) fundamental analysis — Overall grade F based on profitability, financial health, valuation and cash flow. Graham's Fair Value: N/A (negative EPS). Gross profit margin: 39.5%. Operating margin: -568.3%. Net margin: -450.4%. Market cap: $23.0B. Sector: Healthcare. Industry: Biotechnology. Analysis powered by 360investing — free fundamental stock analysis based on Benjamin Graham and Warren Buffett principles.

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