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BioNTech SE

NASDAQ · Healthcare
BioNTech SE
BNTX · Biotechnology
$99.17
▲ 1.63 (1.67%)
Data cached · refreshes every 10 min
Insufficient data to generate a complete Graham analysis.
Overall Grade
F
Defensive
F
Enterprising
Profitability F
Gross Profit Margin 77.6%
Operating Margin -22.3%
Net Income Margin -39.6%
Fin. Health C
Years to Pay Off Debt -0.2 yrs
Working Capital vs Long-Term Debt $13.8B
Working Capital $14.0B
Valuation B
Price-to-Book 1.30x
Cash Flow F
Free Cash Flow -$293M
Owner Earnings -$4M
3/7
Graham Score
Speculative
Defensive — Graham's strict criteria (P/B, P/E, dividends, stability)  ·  Enterprising — Profitability & cash flow focused, accepts higher valuations for quality
Metric Explanations
What each dimension measures and where the thresholds come from.
Gross Profit Margin
Revenue minus cost of goods sold. Graham's ≥40% threshold identifies businesses with durable pricing power. Note: software and financial companies naturally exceed this; retailers and manufacturers rarely reach it due to their cost structures.
Operating Margin
Profit after operating costs before interest and taxes. A consistent ≥15% operating margin signals a business with real competitive advantages. Capital-intensive industries (airlines, auto, commodities) rarely hit this threshold due to their structural cost base — compare within industry for context.
Net Income Margin
Bottom-line profit as a percentage of revenue. The ≥20% target reflects Buffett's preference for highly profitable businesses. Financial engineering (buybacks, tax optimisation) can inflate this temporarily — look for consistency across multiple years rather than a single strong result.
Years to Pay Off Debt
Total Debt ÷ Net Income. Lower = stronger balance sheet. Important caveat: utilities, telecoms, REITs, and infrastructure companies carry large structural debt by design — their bond-like cash flows service it comfortably at ratios that would alarm Graham. Compare within sector.
Working Capital vs Long-Term Debt
Working Capital minus Long-Term Debt. Negative results are common and expected in capital-return-focused businesses like Apple, Domino's, and McDonald's — where aggressive buybacks and dividends intentionally reduce book equity. This does not indicate financial distress in high-FCF businesses.
Working Capital
Current Assets minus Current Liabilities. Negative working capital can be a deliberate efficiency strategy in businesses that collect cash before paying suppliers (retailers, fast food franchises, subscription businesses). Assess alongside free cash flow generation for full context.
Price-to-Book
Market price vs book value per share. Rarely below 1.5x for quality businesses today. Intangible assets (brand, software, patents) don't appear on the balance sheet under accounting rules, making P/B artificially high for asset-light companies. Negative P/B indicates book equity has been reduced by buybacks — common in highly profitable capital-return businesses.
Free Cash Flow
Operating cash flow minus capital expenditures. Buffett's most important metric — cash a business actually generates for its owners after maintaining and growing its asset base. Consistently positive FCF is one of the strongest indicators of a durable, well-run business regardless of accounting profits.
Owner Earnings
Net Income + Depreciation & Amortisation − Capital Expenditures. Buffett's preferred measure of a company's true annual earning power — what could theoretically be distributed to owners without impairing the business. More reliable than reported EPS because it accounts for the capital cost of maintaining the business.
Market Cap $25.1B
Enterprise Value $9.9B
P/E (TTM) -22.20
Dividend Yield N/A
Exchange NASDAQ
Gross Profit 77.6%
Operating Margin -22.3%
Net Margin -39.6%
Sector Healthcare
Industry Biotechnology
Employees 7807
Country Germany
About BioNTech SE

BioNTech SE, together with its subsidiaries, engages in the development and commercialization of immunotherapies in Germany. The company offers BNT162, an mRNA vaccine for the treatment of SARS-CoV-2 virus. It also develops oncology drugs under Phase III clinical trial, including Gotistobart for metastatic non-small cell lung cancer, Pumitamig for small cell lung cancer and advanced/metastatic triple-negative breast cancer, and Trastuzumab pamirtecan for metastatic breast cancer and epirubicin and cyclophosphamide; and drugs under Phase 2/3 clinical trial, such as BNT113 for human papillomavirus and head and neck squamous cell carcinoma, as well as Pumitamig for metastatic colorectal and non-small cell lung cancer. In addition, the company engages in the development of oncology drugs under Phase II clinical trial comprising BNT116 for advance non-small cell lung cancer, BNT326/YL202 for multiple solid tumors and advanced/metastatic breast cancer, Autogene cevumeran for advance colorectal cancer, and Gotistobart for platinum-resistant ovarian cancer, as well as Pumitamig for glioblastoma, hepatocellular carcinoma, malignant pleural mesothelioma, neuroendocrine neoplasms, and metastatic pancreatic ductal adenocarcinoma. Further, it develops BNT166 which is Phase II clinical trial for mpox virus; and infectious diseases drugs under Phase 1/2 clinical trial, which include BNT162 + BNT161 for SARS-CoV-2 and influenza, BNT164 for tuberculosis, BNT165 for malaria, and BNT166 for mpox. The company was incorporated in 2008 and is headquartered in Mainz, Germany.

Showing Key Metrics
Income Highlights
Metric 2025 2024 2023 2022 2021
Gross Profit % 77.6% 80.3% 84.3% 82.7% N/A
Operating Margin % -22.3% -25.8% 22.9% 71.1% N/A
Net Income % -39.6% -24.2% 24.4% 54.5% N/A
Diluted EPS -4.70 -2.77 3.83 37.77 N/A
Balance Sheet Highlights
Metric 2025 2024 2023 2022 2021
Total Assets $22.0B $22.5B $23.0B $23.3B N/A
Total Debt $267M $254M $219M $212M N/A
Working Capital $14.0B $16.3B $17.5B $19.0B N/A
Years to Pay Debt -0.24 -0.38 0.24 0.02 N/A
Cash Flow Highlights
Metric 2025 2024 2023 2022 2021
Free Cash Flow -$293M -$245M $4.7B $13.2B N/A
Owner Earnings -$4M $85M $1.8B $9.9B N/A
CapEx % of Net Income N/A N/A 75.8% 3.9% N/A
These metrics estimate what BioNTech SE is worth based on its fundamentals — independent of what the market currently prices it at. Graham's Fair Value and NCAV are conservative floors rooted in 1930s–60s principles. EPV assumes zero growth. None are price targets — they are reference points for judging whether the current price offers a margin of safety.
Graham's Fair Value
N/A (negative EPS)
Margin of Safety
Market Cap ÷ Company Value
1.01

P/B Ratio
1.30
Warren's Owner Earnings
-$4M
Latest fiscal year
Graham's 7 Criteria
Defensive Investor Checklist
3/7 — Speculative Investor
Adequate Size
$2.9B
vs > $1.5B revenue
Strong Financial Condition
7.54x
vs Current Ratio > 2.0x
Earnings Stability
2 loss years (4 yrs data)
vs No negative EPS years
Dividend Record
No dividend
vs Uninterrupted dividends
Earnings Growth
-89.9% EPS growth
vs > 33% EPS growth
Moderate P/E Ratio
-22.2x
vs P/E ≤ 15.0x
Moderate Price-to-Book
1.30x P/B (P/E×P/B: -29.0)
vs P/B ≤ 1.5x | P/E × P/B ≤ 22.5
Graham's 7 Criteria — Explained
What each criterion measures and why it may or may not apply to modern businesses.
✅ Adequate Size — $2.9B vs > $1.5B revenue
Graham required companies large enough to withstand economic downturns. This threshold ($1.5B) is inflation-adjusted from Graham's original $100M — virtually all S&P 500 companies pass this today.
"The minimum size of an enterprise should be not less than $100 million of annual sales."
✅ Strong Financial Condition — 7.54x vs Current Ratio > 2.0x
Current assets must be at least twice current liabilities. Note: highly profitable companies (Apple, Domino's) often run negative or low working capital deliberately — they collect cash fast and stretch payables. A failing score here is not always a warning sign.
"For industrial companies, current assets should be at least twice current liabilities."
❌ Earnings Stability — 2 loss years (4 yrs data) vs No negative EPS years
Graham required uninterrupted positive earnings. Any loss year is a red flag for defensive investors. Growth companies and cyclicals may show occasional losses during investment cycles or downturns without being fundamentally unsound.
"The company should have shown no deficit in the past ten years."
❌ Dividend Record — No dividend vs Uninterrupted dividends
Graham valued dividends as evidence of financial discipline and shareholder alignment. Many excellent modern businesses (Alphabet, Amazon, Berkshire Hathaway) pay no dividend, preferring to reinvest cash at high rates of return. Failing this criterion does not indicate a poor business — it may indicate a high-growth one.
"Some current dividend payments — for at least the past 20 years."
❌ Earnings Growth — -89.9% EPS growth vs > 33% EPS growth
EPS grew from $37.77 to $3.83 over 1 years. Graham's 33% threshold was set over a 10-year period. Measured over fewer years (as here), the bar is proportionally lower. Share buybacks can also inflate EPS growth without reflecting underlying business improvement.
"A minimum increase of at least one-third in per-share earnings over ten years."
❌ Moderate P/E Ratio — -22.2x vs P/E ≤ 15.0x
Graham's 15x P/E threshold was calibrated to 1960s market averages when interest rates were higher. Today's lower rate environment structurally supports higher multiples — the S&P 500 long-run average P/E is now closer to 20–25x. A stock trading at 20x is not automatically speculative in the modern context.
"The price-earnings ratio should be no more than 15 times average earnings."
✅ Moderate Price-to-Book — 1.30x P/B (P/E×P/B: -29.0) vs P/B ≤ 1.5x | P/E × P/B ≤ 22.5
Graham's 1.5x P/B threshold made sense when most company value was tangible. Today, intangible assets — brand, software, patents, network effects — rarely appear on the balance sheet. A high P/B in tech, pharma, or consumer brands often reflects intangible value, not overvaluation. P/FCF or EV/EBITDA are more reliable for asset-light businesses.
"The price should not be more than 1½ times book value. P/E × P/B ≤ 22.5."
Net Current Asset Value
$52.92
Trading at 1.9x NCAV. Expected for most quality businesses — NCAV was designed to find depression-era bargains and rarely applies to modern profitable companies.
"Buy at two-thirds of net current assets." — Graham
Earnings Power Value
$-28.15
Per share, no-growth floor. Compare to current price.
Cash Flow Analysis
Metric 2025 2024 2023 2022 2021
Capital Expenditure % of Net Income N/A N/A 75.8% 3.9% N/A
Repurchase of Capital Stock $0M $0M -$738M -$986M N/A
Free Cash Flow -$293M -$245M $4.7B $13.2B N/A
Warren's Owner Earnings -$4M $85M $1.8B $9.9B N/A
Peers & Industry Comparison
Biotechnology — Auto-detected peers
Company Price Market Cap P/E Gross Margin Net Margin Revenue
BNTX $99.17 $25.1B -22.20 77.6% -39.6% $2.9B
AMGN
Amgen Inc.
$322.97 $174.3B 22.5 71.4% 21.0% $37.2B
GILD
Gilead Sciences, Inc.
$132.63 $164.6B 19.6 78.8% 28.9% $29.4B
BIIB
Biogen Inc.
$186.97 $27.6B 20.1 78.7% 13.8% $9.9B
REGN
Regeneron Pharmaceuticals, Inc.
$708.53 $74.3B 17.3 43.9% 29.6% $14.9B
VRTX
Vertex Pharmaceuticals Incorpor
$428.88 $109.1B 28.0 53.7% 32.9% $12.0B
"The management of a business is its most important single factor — more important than market position, patents, or financial structure."
— Benjamin Graham
Capital Allocation & Alignment
Insider Ownership
57.43%
High — management has strong skin in the game
Return on Equity (ROE)
-5.9%
Weak — poor returns on equity
Return on Assets (ROA)
-5.2%
Poor — assets are not generating adequate returns
Debt Trend YoY
+5.2% YoY
Debt is roughly stable
Leadership Team
Ugur Sahin
Co-Founder, CEO & Chair of the Management Board
Age 60
Pay: $1,237,199
Ozlem Tureci
Co-Founder, Chief Medical Officer & Member of Management Board
Age 58
Pay: $986,241
Ramon Zapata-Gomez
CFO & Member of Management Board
Age 51
Pay: $1,199,672
Sierk Pötting Ph.
MD, COO & Member of Management Board
Age 52
Pay: $1,017,904
Lisa Birringer
Senior Vice President of Global Financial Reporting & Accounting
Top Institutional Holders
Institution % Owned Shares
FMR, LLC 2.35% 5,933,594
T. Rowe Price Investment Management, Inc. 1.77% 4,484,599
Primecap Management Company 1.50% 3,800,011
Flossbach von Storch SE 1.46% 3,680,315
Dodge & Cox Inc. 1.43% 3,614,491
BNP Paribas Financial Markets 0.62% 1,578,094
Temasek Holdings (Private) Ltd 0.60% 1,506,027
Jane Street Group, LLC 0.54% 1,361,221
Risk Analysis
Beta (Market Risk)
1.37
Moderate volatility — moves slightly more than market
Short Interest
4.7% of float
Low short interest — market is not heavily bearish
Debt-to-Equity
0.01x
Conservative balance sheet — low financial risk
Current Ratio
7.54x
Strong liquidity — Graham approved
52-Week Price Range
Low: $79.52 Current: $99.17 High: $124.00
Currently at 44% of 52-week range

BioNTech SE (BNTX) fundamental analysis — Overall grade F based on profitability, financial health, valuation and cash flow. Graham's Fair Value: N/A (negative EPS). Gross profit margin: 77.6%. Operating margin: -22.3%. Net margin: -39.6%. Market cap: $25.1B. Sector: Healthcare. Industry: Biotechnology. Analysis powered by 360investing — free fundamental stock analysis based on Benjamin Graham and Warren Buffett principles.

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