BioNTech SE, together with its subsidiaries, engages in the development and commercialization of immunotherapies in Germany. The company offers BNT162, an mRNA vaccine for the treatment of SARS-CoV-2 virus. It also develops oncology drugs under Phase III clinical trial, including Gotistobart for metastatic non-small cell lung cancer, Pumitamig for small cell lung cancer and advanced/metastatic triple-negative breast cancer, and Trastuzumab pamirtecan for metastatic breast cancer and epirubicin and cyclophosphamide; and drugs under Phase 2/3 clinical trial, such as BNT113 for human papillomavirus and head and neck squamous cell carcinoma, as well as Pumitamig for metastatic colorectal and non-small cell lung cancer. In addition, the company engages in the development of oncology drugs under Phase II clinical trial comprising BNT116 for advance non-small cell lung cancer, BNT326/YL202 for multiple solid tumors and advanced/metastatic breast cancer, Autogene cevumeran for advance colorectal cancer, and Gotistobart for platinum-resistant ovarian cancer, as well as Pumitamig for glioblastoma, hepatocellular carcinoma, malignant pleural mesothelioma, neuroendocrine neoplasms, and metastatic pancreatic ductal adenocarcinoma. Further, it develops BNT166 which is Phase II clinical trial for mpox virus; and infectious diseases drugs under Phase 1/2 clinical trial, which include BNT162 + BNT161 for SARS-CoV-2 and influenza, BNT164 for tuberculosis, BNT165 for malaria, and BNT166 for mpox. The company was incorporated in 2008 and is headquartered in Mainz, Germany.
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Gross Profit % | 77.6% ▼ | 80.3% | 84.3% | 82.7% | N/A |
| Operating Margin % | -22.3% ▲ | -25.8% | 22.9% | 71.1% | N/A |
| Net Income % | -39.6% ▼ | -24.2% | 24.4% | 54.5% | N/A |
| Diluted EPS | -4.70 ▼ | -2.77 | 3.83 | 37.77 | N/A |
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Total Assets | $22.0B | $22.5B | $23.0B | $23.3B | N/A |
| Total Debt | $267M ↑ | $254M | $219M | $212M | N/A |
| Working Capital | $14.0B ▼ | $16.3B | $17.5B | $19.0B | N/A |
| Years to Pay Debt | -0.24 | -0.38 | 0.24 | 0.02 | N/A |
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Free Cash Flow | -$293M ▼ | -$245M | $4.7B | $13.2B | N/A |
| Owner Earnings | -$4M | $85M | $1.8B | $9.9B | N/A |
| CapEx % of Net Income | N/A | N/A | 75.8% | 3.9% | N/A |
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|
| Capital Expenditure % of Net Income | N/A | N/A | 75.8% | 3.9% | N/A |
| Repurchase of Capital Stock | $0M | $0M | -$738M | -$986M | N/A |
| Free Cash Flow | -$293M ▼ | -$245M ▼ | $4.7B ▼ | $13.2B • | N/A • |
| Warren's Owner Earnings | -$4M | $85M | $1.8B | $9.9B | N/A |
| Company | Price | Market Cap | P/E | Gross Margin | Net Margin | Revenue |
|---|---|---|---|---|---|---|
| BNTX | $99.17 | $25.1B | -22.20 | 77.6% | -39.6% | $2.9B |
| AMGN Amgen Inc. |
$322.97 | $174.3B | 22.5 | 71.4% | 21.0% | $37.2B |
| GILD Gilead Sciences, Inc. |
$132.63 | $164.6B | 19.6 | 78.8% | 28.9% | $29.4B |
| BIIB Biogen Inc. |
$186.97 | $27.6B | 20.1 | 78.7% | 13.8% | $9.9B |
| REGN Regeneron Pharmaceuticals, Inc. |
$708.53 | $74.3B | 17.3 | 43.9% | 29.6% | $14.9B |
| VRTX Vertex Pharmaceuticals Incorpor |
$428.88 | $109.1B | 28.0 | 53.7% | 32.9% | $12.0B |
| Institution | % Owned | Shares |
|---|---|---|
| FMR, LLC | 2.35% | 5,933,594 |
| T. Rowe Price Investment Management, Inc. | 1.77% | 4,484,599 |
| Primecap Management Company | 1.50% | 3,800,011 |
| Flossbach von Storch SE | 1.46% | 3,680,315 |
| Dodge & Cox Inc. | 1.43% | 3,614,491 |
| BNP Paribas Financial Markets | 0.62% | 1,578,094 |
| Temasek Holdings (Private) Ltd | 0.60% | 1,506,027 |
| Jane Street Group, LLC | 0.54% | 1,361,221 |
BioNTech SE (BNTX) fundamental analysis — Overall grade F based on profitability, financial health, valuation and cash flow. Graham's Fair Value: N/A (negative EPS). Gross profit margin: 77.6%. Operating margin: -22.3%. Net margin: -39.6%. Market cap: $25.1B. Sector: Healthcare. Industry: Biotechnology. Analysis powered by 360investing — free fundamental stock analysis based on Benjamin Graham and Warren Buffett principles.
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