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Gilead Sciences, Inc.

Data period: Annual Quarterly Graham uses annual
NASDAQ · Healthcare
Gilead Sciences, Inc.
GILD · Drug Manufacturers - General
$150.56
▲ 0.45 (0.3%)
Cached · 10 min
Overall Grade
F
Defensive
F
Enterprising
Profitability
F
Gross Profit Margin 79.8%
Operating Margin 32.5%
Net Income Margin -134.5%
Fin. Health
D
Years to Pay Off Debt -2.5 yrs
Working Capital vs Long-Term Debt -$20.9B
Working Capital $2.9B
Valuation
F
Price-to-Book 15.78x
Cash Flow
C
Free Cash Flow $3.4B
Owner Earnings -$9.7B
About Gilead Sciences, Inc.
Gilead Sciences, Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines in the areas of unmet medical need in the United States, Europe, and internationally. The company provides Biktarvy, Descovy, Genvoya, Odefsey, Sunlenca, Symtuza, and YeztugoFor the treatment of HIV-1 infection in patients. It also provides Epclusa, Livdelzi, and Vemlidy to treat chronic hepatitis C virus, primary biliary cholangitis, and chronic hepatitis B virus; Tecartus, a T-cell therapy for the treatment of adult patients; Trodelvy, an injection for intravenous use; and Yescarta, a suspension for intravenous infusion, is a CAR T-cell therapy for the treatment of adult patients. Further, it provides AmBisome, for the treatment of serious invasive fungal infections; and Veklury for the treatment of COVID-19. Additionally, the company engages in the development of various immunotherapies for patients with cancer and other incurable diseases. The company has collaboration agreements with Shenzhen Pregene Biopharma Co., Ltd.; Abingworth; Arcus Biosciences, Inc.; Merck Sharp & Dohme Corp.; Janssen Sciences Ireland Unlimited Company; Japan Tobacco, Inc.; Everest Medicines; Merck & Co, Inc.; Tentarix Biotherapeutics Inc.; and Assembly Biosciences, Inc. It also has research collaboration, option, and license agreement with Merus N.V. for the discovery of novel dual tumor-associated antigens (TAA) targeting trispecific antibodies. The company has a collaboration with Terray Therapeutics, Inc. to discover and develop small molecule therapies; and LEO Pharma to develop, manufacture, and commercialize the small molecule oral STAT6 program. The company has a partnership with Pan American Health Organization (PAHO) to accelerate access to lenacapavir for HIV prevention as pre-exposure prophylaxis (PrEP) across all PAHO member states in Latin America and the Caribbean. The company was incorporated in 1987 and is headquartered in Foster City, California.
Metric Explanations
What each dimension measures and where the thresholds come from.
Gross Profit Margin
Revenue minus cost of goods sold. Graham's ≥40% threshold identifies businesses with durable pricing power. Note: software and financial companies naturally exceed this; retailers and manufacturers rarely reach it due to their cost structures.
Operating Margin
Profit after operating costs before interest and taxes. A consistent ≥15% operating margin signals a business with real competitive advantages. Capital-intensive industries (airlines, auto, commodities) rarely hit this threshold due to their structural cost base — compare within industry for context.
Net Income Margin
Bottom-line profit as a percentage of revenue. The ≥20% target reflects Buffett's preference for highly profitable businesses. Financial engineering (buybacks, tax optimisation) can inflate this temporarily — look for consistency across multiple years rather than a single strong result.
Years to Pay Off Debt
Total Debt ÷ Net Income. Lower = stronger balance sheet. Important caveat: utilities, telecoms, REITs, and infrastructure companies carry large structural debt by design — their bond-like cash flows service it comfortably at ratios that would alarm Graham. Compare within sector.
Working Capital vs Long-Term Debt
Working Capital minus Long-Term Debt. Negative results are common and expected in capital-return-focused businesses like Apple, Domino's, and McDonald's — where aggressive buybacks and dividends intentionally reduce book equity. This does not indicate financial distress in high-FCF businesses.
Working Capital
Current Assets minus Current Liabilities. Negative working capital can be a deliberate efficiency strategy in businesses that collect cash before paying suppliers (retailers, fast food franchises, subscription businesses). Assess alongside free cash flow generation for full context.
Price-to-Book
Market price vs book value per share. Rarely below 1.5x for quality businesses today. Intangible assets (brand, software, patents) don't appear on the balance sheet under accounting rules, making P/B artificially high for asset-light companies like software and consumer brands.
Free Cash Flow
Operating cash flow minus capital expenditures. Buffett's most important metric — cash a business actually generates for its owners after maintaining and growing its asset base. Consistently positive FCF is one of the strongest indicators of a durable, well-run business regardless of accounting profits.
Owner Earnings
Net Income + Depreciation & Amortisation − Capital Expenditures. Buffett's preferred measure of a company's true annual earning power — what could theoretically be distributed to owners without impairing the business. More reliable than reported EPS because it accounts for the capital cost of maintaining the business.
Market Cap $186.7B
Enterprise Value $208.0B
P/E (TTM) 15.22
Dividend Yield 2.15%
Exchange NASDAQ
Gross Profit 79.8%
Operating Margin 32.5%
Net Margin -134.5%
Sector Healthcare
Industry Drug Manufacturers - General
Employees 17000
Country United States
Showing Key Metrics
Income Highlights
Metric Q2 2026 Q4 2025 Q4 2024
Gross Profit % 79.8% 79.5% N/A
Operating Margin % 32.5% 37.7% N/A
Net Income % -134.5% 27.5% N/A
Diluted EPS -8.45 1.74 N/A
Balance Sheet Highlights
Metric Q2 2026 Q4 2025 Q4 2024
Total Assets $49.4B $59.0B N/A
Total Debt $26.2B $24.9B N/A
Working Capital $2.9B $6.5B N/A
Years to Pay Debt -2.50 11.42 N/A
Cash Flow Highlights
Metric Q2 2026 Q4 2025 Q4 2024
Free Cash Flow $3.4B $3.1B N/A
Owner Earnings -$9.7B $3.1B N/A
CapEx % of Net Income N/A 9.4% N/A
📊 Quarterly mode — Graham Fair Value & 7 Criteria require annual data. Switch to Annual for full analysis.
Quarter vs Same Quarter Last Year
YoY strips seasonality
Revenue Growth (YoY)
Prior year: $7.1B ▲ $7.8B +10.2%
Revenue growth vs same quarter last year strips seasonality. Consistent double-digit growth is a Buffett hallmark.
Gross Margin
Prior year: 78.8% ▲ 79.8% +1.0pp
Buffett: consistent gross margin above 40% signals durable pricing power and competitive moat.
Operating Margin
Prior year: 35.9% ▼ 32.5% -3.3pp
Graham: operating margin reflects true business economics before financing. Trend matters as much as level.
Net Margin
Prior year: 27.7% ▼ -134.5% -162.2pp
Net margin can be distorted by one-time items, tax timing, or interest costs — compare to operating margin for signal quality.
Quarterly Health Checks
3 Graham/Buffett criteria that are valid and reliable on quarterly data
✅ Adequate Size
Graham required scale for resilience. Quarterly revenue × 4 gives an annualised proxy.
$7.8B/qtr (≈$31.2B ann.)
vs > $1.5B annualised revenue
❌ Financial Condition
Current assets vs current liabilities — a real-time liquidity snapshot. Valid and reliable on quarterly data.
1.27x current ratio
vs ≥ 2.0x
✅ Free Cash Flow
Buffett's most important single metric. A positive FCF quarter means the business generated real cash for owners after maintaining its asset base.
$3.4B
vs Positive
Operating Cash Flow
$3.6B
Latest quarter · Buffett's cash reality check
ROIC
5.2%
Based on latest annual operating income
Return on Invested Capital — Buffett's preferred measure for asset-light businesses. ROIC > 15% consistently signals a durable competitive advantage (moat). More meaningful than P/B for software, pharma, and consumer brand companies where most value is intangible and off-balance-sheet.
Market Cap / Net Assets
15.9x
Net Assets: $11.7B
⚠️ Net margin compressed 162.2pp vs same quarter last year. Common causes: one-time charges (restructuring, write-downs, legal settlements), tax rate changes, or rising interest expense. Check the income statement notes before drawing conclusions about operating health.
⚠️ Operating income is positive but net income is negative. This typically reflects below-the-line items: interest expense, impairment charges, tax adjustments, or one-time write-offs. The core business may be healthy — operating margin is a better signal of ongoing profitability here.
⚠️ Revenue grew vs prior year but operating margin contracted. Possible explanations: deliberate investment in growth (hiring, marketing, R&D), input cost inflation, or pricing pressure from competition. Buffett distinguishes between spending that builds moat vs. spending that doesn't.
Peers & Industry
No auto-detected peers for Drug Manufacturers - General. You can manually compare GILD against any stock using the Compare tool.
"The management of a business is its most important single factor — more important than market position, patents, or financial structure."
— Benjamin Graham
Capital Allocation & Alignment
Insider Ownership
0.11%
Low — management has little skin in the game
Return on Equity (ROE)
-88.7%
Weak — poor returns on equity
Return on Assets (ROA)
-21.3%
Poor — assets are not generating adequate returns
Share Buybacks (Latest Year)
$1.9B
Management is returning capital to shareholders via buybacks
Debt Trend YoY
+18.4% YoY
Debt is growing — management is leveraging up
Leadership Team
Daniel Patrick O'Day
Chairman & CEO
Age 60
Pay: $8,698,736
Andrew Dickinson
Executive VP & CFO
Age 55
Pay: $3,143,899
Jacquie Ross
Senior Vice President of Treasury & Investor Relations
Jyoti Mehra
Executive Vice President of Human Resources
Age 48
Linda Slanec Higgins Ph.
Senior Vice President of Research, Innovation & Portfolio
Age 63
Top Institutional Holders
Institution % Owned Shares
Blackrock Inc. 9.83% 121,844,108
Vanguard Capital Management LLC 6.54% 81,091,734
FMR, LLC 5.39% 66,870,816
State Street Corporation 4.94% 61,216,552
Capital World Investors 3.31% 40,988,975
Invesco Ltd. 3.21% 39,819,151
Vanguard Portfolio Management LLC 2.85% 35,316,168
Geode Capital Management, LLC 2.42% 30,065,642
Risk Analysis
Beta (Market Risk)
0.35
Low volatility — more stable than the market
Short Interest
1.9% of float
Low short interest — market is not heavily bearish
Debt-to-Equity
2.23x
High leverage — significant financial risk
Current Ratio
1.26x
Adequate liquidity
52-Week Price Range
Low: $108.46 Current: $150.56 High: $157.29
Currently at 86% of 52-week range

Gilead Sciences, Inc. (GILD) fundamental analysis — Overall grade F based on profitability, financial health, valuation and cash flow. Graham's Fair Value: N/A (negative EPS). Gross profit margin: 79.8%. Operating margin: 32.5%. Net margin: -134.5%. Market cap: $186.7B. Sector: Healthcare. Industry: Drug Manufacturers - General. Analysis powered by 360investing — free fundamental stock analysis based on Benjamin Graham and Warren Buffett principles.

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